Structured Summary
Abstract
A benzodiazepine derivative that is a long-acting GABA-A RECEPTOR agonist. It is used as an antiepileptic in the treatment of SEIZURES, including seizures associated with LENNOX-GASTAUT SYNDROME. It is also used as an anxiolytic, for the short-term treatment of acute ANXIETY.
Chemical Identity
Chemical Information
- Molecular Formula
- C16H13ClN2O2
- Molecular Weight
- 300.74 g/mol
- CAS Registry No.
- 22316-47-8
- IUPAC Name
- 7-chloro-1-methyl-5-phenyl-1,5-benzodiazepine-2,4-dione
- InChIKey
- CXOXHMZGEKVPMT-UHFFFAOYSA-N
- SMILES
- CN1C(=O)CC(=O)N(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3
- MeSH Unique ID
- D000078306
- Source
- PubChem CID 2789
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
Drug Class
Pharmacological Action
MeSH Record
Synonyms
8 entry terms
- 1-Phenyl-5-methyl-8-chloro-1,2,4,5- tetrahydro-2,4-diketo-3H-1,5-benzodiazepine
- Frisium
- HR 376
- LM-2717
- Onfi
- Urbanyl
- LM 2717
- LM2717
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2019 (1976)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Clobazam. Medical Subject Headings (MeSH). 2026. Unique ID D000078306. http://id.nlm.nih.gov/mesh/2026/D000078306
- Clobazam. In: Wikipedia. https://en.wikipedia.org/wiki/Clobazam
- Clobazam. In: Wikidata. https://www.wikidata.org/wiki/Q412164
- Clobazam. In: PubChem Compound. CID 2789. https://pubchem.ncbi.nlm.nih.gov/compound/2789