Chemicals and Drugs

Cleavage Stimulation Factor

A RNA-binding protein that stimulates the cleavage of the 3' end of MRNA near the POLYADENYLATION site. It is a heterotrimer of 55-, 64- and 77-kDa subunits and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A RNA-binding protein that stimulates the cleavage of the 3' end of MRNA near the POLYADENYLATION site. It is a heterotrimer of 55-, 64- and 77-kDa subunits and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.

MeSH Record

Classification

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MeSH Record

Synonyms

1 entry terms
  • CstF Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2003; for CLEAVAGE STIMULATION FACTOR use MRNA CLEAVAGE AND POLYADENYLATION FACTORS (NM) 1992-2002

MeSH Record

Previous Indexing

  • RNA-Binding Proteins (1992-2002)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Cleavage Stimulation Factor. Medical Subject Headings (MeSH). 2026. Unique ID D039241. http://id.nlm.nih.gov/mesh/2026/D039241
  2. Cleavage Stimulation Factor. In: Wikipedia. https://en.wikipedia.org/wiki/Cleavage_stimulation_factor
  3. Cleavage Stimulation Factor. In: Wikidata. https://www.wikidata.org/wiki/Q22326127