Chemicals and Drugs

Claudin-5

A claudin subtype that is found localized to TIGHT JUNCTIONS in VASCULAR ENDOTHELIAL CELLS. The protein was initially identified as one of several proteins which are deleted in VELOCARDIOFACIAL SYNDROME and may play an important role in maintaining the integrity of the BLOOD-BRAIN BARRIER.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A claudin subtype that is found localized to TIGHT JUNCTIONS in VASCULAR ENDOTHELIAL CELLS. The protein was initially identified as one of several proteins which are deleted in VELOCARDIOFACIAL SYNDROME and may play an important role in maintaining the integrity of the BLOOD-BRAIN BARRIER.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

3 entry terms
  • Claudin 5
  • TMVCF Protein
  • Transmembrane Protein Deleted in Velocardiofacial Syndrome

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2013

MeSH Record

Previous Indexing

  • Claudins (2011-2012)
  • Membrane Proteins (1997-2010)

MeSH Hierarchy

Tree Number

  1. D12.776w.543w.940w.200w.500

AMA Style

References

  1. National Library of Medicine. Claudin-5. Medical Subject Headings (MeSH). 2026. Unique ID D062507. http://id.nlm.nih.gov/mesh/2026/D062507
  2. Claudin-5. In: Wikidata. https://www.wikidata.org/wiki/Q24783584