Chemicals and Drugs

Claudin-1

An integral membrane protein that is localized to TIGHT JUNCTIONS, where it plays a role in controlling the paracellular permeability of polarized cells. Mutations in the gene for claudin-1 are associated with Neonatal Ichthyosis-Sclerosing Cholangitis (NISCH) Syndrome.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An integral membrane protein that is localized to TIGHT JUNCTIONS, where it plays a role in controlling the paracellular permeability of polarized cells. Mutations in the gene for claudin-1 are associated with Neonatal Ichthyosis-Sclerosing Cholangitis (NISCH) Syndrome.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

1 entry terms
  • Claudin 1

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2013

MeSH Hierarchy

Tree Number

  1. D12.776w.543w.940w.200w.100

AMA Style

References

  1. National Library of Medicine. Claudin-1. Medical Subject Headings (MeSH). 2026. Unique ID D062445. http://id.nlm.nih.gov/mesh/2026/D062445
  2. Claudin-1. In: Wikidata. https://www.wikidata.org/wiki/Q24782855