Structured Summary
Abstract
An antineoplastic agent used in the treatment of lymphoproliferative diseases including hairy-cell leukemia.
Chemical Identity
Chemical Information
- Molecular Formula
- C10H12ClN5O3
- Molecular Weight
- 285.69 g/mol
- CAS Registry No.
- 4291-63-8
- IUPAC Name
- (2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
- InChIKey
- PTOAARAWEBMLNO-KVQBGUIXSA-N
- SMILES
- C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=C(N=C32)Cl)N)CO)O
- MeSH Unique ID
- D017338
- Source
- PubChem CID 20279
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
4 entry terms
- 2'-Deoxy-2-chloroadenosine
- 2-Chloro-2'-deoxyadenosine
- 2-Chlorodeoxyadenosine
- Leustatin
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
95; was 2-CHLORODEOXYADENOSINE 1993-94; was 2-CHLORO-2'-DEOXYADENOSINE (NM) 1986-92
MeSH Record
Previous Indexing
- 2-Chloroadenosine/analogs & derivatives (1986-1992)
- Deoxyadenosines (1986-1992)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Cladribine. Medical Subject Headings (MeSH). 2026. Unique ID D017338. http://id.nlm.nih.gov/mesh/2026/D017338
- Cladribine. In: Wikipedia. https://en.wikipedia.org/wiki/Cladribine
- Cladribine. In: Wikidata. https://www.wikidata.org/wiki/Q414030
- Cladribine. In: PubChem Compound. CID 20279. https://pubchem.ncbi.nlm.nih.gov/compound/20279