Structured Summary
Abstract
A quinoline and tetrazole derivative that acts as a phosphodiesterase type 3 inhibitor, with anti-platelet and vasodilating activity. It is used in the treatment of PERIPHERAL VASCULAR DISEASES; ISCHEMIC HEART DISEASE; and in the prevention of stroke.
Chemical Identity
Chemical Information
- Molecular Formula
- C20H27N5O2
- Molecular Weight
- 369.5 g/mol
- CAS Registry No.
- 73963-72-1
- IUPAC Name
- 6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one
- InChIKey
- RRGUKTPIGVIEKM-UHFFFAOYSA-N
- SMILES
- C1CCC(CC1)N2C(=NN=N2)CCCCOC3=CC4=C(C=C3)NC(=O)CC4
- MeSH Unique ID
- D000077407
- Source
- PubChem CID 2754
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
4 entry terms
- 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone
- OPC 13013
- OPC-13013
- Pletal
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2019 (1985)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Cilostazol. Medical Subject Headings (MeSH). 2026. Unique ID D000077407. http://id.nlm.nih.gov/mesh/2026/D000077407
- Cilostazol. In: Wikipedia. https://en.wikipedia.org/wiki/Cilostazol
- Cilostazol. In: Wikidata. https://www.wikidata.org/wiki/Q258591
- Cilostazol. In: PubChem Compound. CID 2754. https://pubchem.ncbi.nlm.nih.gov/compound/2754