Chemicals and Drugs

Ciliary Neurotrophic Factor Receptor

Cell surface receptors for CILIARY NEUROTROPHIC FACTOR. They are heterotrimeric proteins formed by the association of the CILIARY NEUROTROPHIC FACTOR RECEPTOR ALPHA SUBUNIT with the LEUKEMIA INHIBITORY FACTOR RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR GP130. Although the receptor regulates neuronal development, it is structurally similar to the cytokine receptor for INTERLEUKIN-6; (RECEPTORS, INTERLEUKIN-6).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Cell surface receptors for CILIARY NEUROTROPHIC FACTOR. They are heterotrimeric proteins formed by the association of the CILIARY NEUROTROPHIC FACTOR RECEPTOR ALPHA SUBUNIT with the LEUKEMIA INHIBITORY FACTOR RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR GP130. Although the receptor regulates neuronal development, it is structurally similar to the cytokine receptor for INTERLEUKIN-6; (RECEPTORS, INTERLEUKIN-6).

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Synonyms

3 entry terms
  • CNTF Receptor
  • Receptor, Ciliary Neurotrophic Factor
  • Receptor, CNTF

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

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History Note

2000; use RECEPTOR, CILIARY NEUROTROPHIC FACTOR (NM) 1991-1999

MeSH Record

Previous Indexing

  • Receptor Protein-Tyrosine Kinases (1997-1999)
  • Receptors, Cell Surface (1991-1999)
  • Receptors, Growth Factor (1993-1994)
  • Receptors, Nerve Growth Factor (1995-1999)

MeSH Hierarchy

Tree Number

  1. D12.776w.543w.750w.750w.400w.550w.250w

AMA Style

References

  1. National Library of Medicine. Ciliary Neurotrophic Factor Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D020801. http://id.nlm.nih.gov/mesh/2026/D020801
  2. Ciliary Neurotrophic Factor Receptor. In: Wikipedia. https://en.wikipedia.org/wiki/Ciliary_neurotrophic_factor_receptor
  3. Ciliary Neurotrophic Factor Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q21108411