Chemicals and Drugs

Chymotrypsin

A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

3 entry terms
  • Alpha-Chymotrypsin Choay
  • Alphacutanée
  • Avazyme

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/antag: consider also ALPHA 1-ANTICHYMOTRYPSIN

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.656w.300w.760.176w
  2. D08.811w.277w.656w.959w.350.176w

AMA Style

References

  1. National Library of Medicine. Chymotrypsin. Medical Subject Headings (MeSH). 2026. Unique ID D002918. http://id.nlm.nih.gov/mesh/2026/D002918
  2. Chymotrypsin. In: Wikipedia. https://en.wikipedia.org/wiki/Chymotrypsin
  3. Chymotrypsin. In: Wikidata. https://www.wikidata.org/wiki/Q383836