Structured Summary
Abstract
A technique with which an unknown region of a chromosome can be explored. It is generally used to isolate a locus of interest for which no probe is available but that is known to be linked to a gene which has been identified and cloned. A fragment containing a known gene is selected and used as a probe to identify other overlapping fragments which contain the same gene. The nucleotide sequences of these fragments can then be characterized. This process continues for the length of the chromosome.
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Synonyms
3 entry terms
- Chromosome Walkings
- Walking, Chromosome
- Walkings, Chromosome
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Aspects Covered
2 allowable subheadings
Indexed with the subheadings instrumentation, methods.
MeSH Record
Indexing Annotation
technique for exploring an unknown region of a CHROMOSOME
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History Note
91
MeSH Record
Previous Indexing
- Chromosome Mapping (1983-1990)
- Cloning, Molecular (1983-1990)
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AMA Style
References
- National Library of Medicine. Chromosome Walking. Medical Subject Headings (MeSH). 2026. Unique ID D016386. http://id.nlm.nih.gov/mesh/2026/D016386
- Chromosome Walking. In: Wikipedia. https://en.wikipedia.org/wiki/Primer_walking
- Chromosome Walking. In: Wikidata. https://www.wikidata.org/wiki/Q3817120