Chemicals and Drugs

Chromomycins

A complex of several closely related glycosidic antibiotics from Streptomyces griseus. The major component, CHROMOMYCIN A3, is used as a fluorescent stain of DNA where it attaches and inhibits RNA synthesis. It is also used as an antineoplastic agent, especially for solid tumors.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A complex of several closely related glycosidic antibiotics from Streptomyces griseus. The major component, CHROMOMYCIN A3, is used as a fluorescent stain of DNA where it attaches and inhibits RNA synthesis. It is also used as an antineoplastic agent, especially for solid tumors.

MeSH Record

Classification

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • Chromomycin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

antineoplastic antibiotics

MeSH Record

History Note

73(72)

MeSH Record

Previous Indexing

  • Antibiotics, Antineoplastic (1967-1971)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Chromomycins. Medical Subject Headings (MeSH). 2026. Unique ID D002865. http://id.nlm.nih.gov/mesh/2026/D002865
  2. Chromomycins. In: Wikidata. https://www.wikidata.org/wiki/Q99050645