Chemicals and Drugs

Chloroquinolinols

8-Hydroxyquinolinols chlorinated on the number 5 and/or 7 carbon atom(s). They are antibacterial, antiprotozoal, and antidiarrheal, especially in amebiasis, and have also been used as antiseborrheics. The compounds are mostly used topically, but have been used also as animal feed additives. They may cause optic and other neuropathies and are most frequently administered in combination with other agents.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

8-Hydroxyquinolinols chlorinated on the number 5 and/or 7 carbon atom(s). They are antibacterial, antiprotozoal, and antidiarrheal, especially in amebiasis, and have also been used as antiseborrheics. The compounds are mostly used topically, but have been used also as animal feed additives. They may cause optic and other neuropathies and are most frequently administered in combination with other agents.

MeSH Record

Classification

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Drug Class

Pharmacological Action

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(65); was see under HYDROXYQUINOLINES 1965-90 (Prov 1965-74)

MeSH Hierarchy

Tree Number

  1. D03w.633.100.810.350.625w.250

AMA Style

References

  1. National Library of Medicine. Chloroquinolinols. Medical Subject Headings (MeSH). 2026. Unique ID D002739. http://id.nlm.nih.gov/mesh/2026/D002739
  2. Chloroquinolinols. In: Wikidata. https://www.wikidata.org/wiki/Q76855556