Structured Summary
Abstract
A lectin that binds CHITIN, but lacks chitinase activity. It may be involved in tissue remodeling and cellular responses to the environment, including the response of type 2 HELPER T-CELLS to INFLAMMATION and sensitization to ALLERGENS. Mutations in the CHI3L1 gene are associated with ASTHMA.
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Classification
Broader headings
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Synonyms
10 entry terms
- CGP-39 Protein
- CHI3L1 Protein
- Cartilage Glycoprotein 39
- GP-39 Protein
- YLK-40 Protein
- CGP 39 Protein
- Chitinase 3 Like Protein 1
- GP 39 Protein
- Glycoprotein 39, Cartilage
- YLK 40 Protein
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- Adipokines (2003-2016)
- Glycoproteins (1993-2016)
- Lectins (2003-2016)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Chitinase-3-Like Protein 1. Medical Subject Headings (MeSH). 2026. Unique ID D000071451. http://id.nlm.nih.gov/mesh/2026/D000071451
- Chitinase-3-Like Protein 1. In: Wikidata. https://www.wikidata.org/wiki/Q24776897