Chemicals and Drugs

Chemokine CCL5

A CC-type chemokine that is a chemoattractant for EOSINOPHILS; MONOCYTES; and LYMPHOCYTES. It is a potent and selective eosinophil chemotaxin that is stored in and released from PLATELETS and activated T-LYMPHOCYTES. Chemokine CCL5 is specific for CCR1 RECEPTORS; CCR3 RECEPTORS; and CCR5 RECEPTORS. The acronym RANTES refers to Regulated on Activation, Normal T Expressed and Secreted.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A CC-type chemokine that is a chemoattractant for EOSINOPHILS; MONOCYTES; and LYMPHOCYTES. It is a potent and selective eosinophil chemotaxin that is stored in and released from PLATELETS and activated T-LYMPHOCYTES. Chemokine CCL5 is specific for CCR1 RECEPTORS; CCR3 RECEPTORS; and CCR5 RECEPTORS. The acronym RANTES refers to Regulated on Activation, Normal T Expressed and Secreted.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

7 entry terms
  • CCL5 Chemokine
  • RANTES
  • RANTES Protein, T-Cell
  • CCL5, Chemokine
  • Chemokine, CCL5
  • RANTES Protein, T Cell
  • T-Cell RANTES Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2008(1996)

MeSH Record

Previous Indexing

  • Lymphokines (1988-1995)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.276.374w.200w.110.250w
  2. D12.776w.467.374w.200w.110.250w
  3. D23.125.300w.110.250w
  4. D23.469.200w.110.250w
  5. D23.529.374w.200w.110.250w

AMA Style

References

  1. National Library of Medicine. Chemokine CCL5. Medical Subject Headings (MeSH). 2026. Unique ID D018946. http://id.nlm.nih.gov/mesh/2026/D018946
  2. Chemokine CCL5. In: Wikipedia. https://en.wikipedia.org/wiki/CCL5
  3. Chemokine CCL5. In: Wikidata. https://www.wikidata.org/wiki/Q3492926