Chemicals and Drugs

Chemokine CCL18

A CC-type chemokine highly expressed in the lungs, lymph nodes, placenta, and bone marrow; it is also expressed by DENDRITIC CELLS in the GERMINAL CENTER, and peripheral blood MACROPHAGES. It functions as a chemotactic factor that specifically attracts LYMPHOCYTES, especially B-Cells, into lymph node follicles, and naive T-cells towards dendritic cells and activated T-cells. It does not attract MONOCYTES or GRANULOCYTES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A CC-type chemokine highly expressed in the lungs, lymph nodes, placenta, and bone marrow; it is also expressed by DENDRITIC CELLS in the GERMINAL CENTER, and peripheral blood MACROPHAGES. It functions as a chemotactic factor that specifically attracts LYMPHOCYTES, especially B-Cells, into lymph node follicles, and naive T-cells towards dendritic cells and activated T-cells. It does not attract MONOCYTES or GRANULOCYTES.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

8 entry terms
  • AMAC-1 Protein
  • MIP-4 Protein
  • Macrophage Inflammatory Protein 4
  • Pulmonary and Activation-Regulated Chemokine
  • AMAC 1 Protein
  • CCL18, Chemokine
  • MIP 4 Protein
  • Pulmonary and Activation Regulated Chemokine

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • Chemokines, CC (1998-2017)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.276.374w.200w.110.100w
  2. D12.644w.276.374w.200w.600w.075w
  3. D12.776w.467.374w.200w.110.100w
  4. D12.776w.467.374w.200w.600w.075w
  5. D23.125.300w.110.100w
  6. D23.125.300w.600w.250w
  7. D23.469.200w.110.100w
  8. D23.469.200w.600w.075w
  9. D23.529.374w.200w.110.100w
  10. D23.529.374w.200w.600w.075w

AMA Style

References

  1. National Library of Medicine. Chemokine CCL18. Medical Subject Headings (MeSH). 2026. Unique ID D000075366. http://id.nlm.nih.gov/mesh/2026/D000075366
  2. Chemokine CCL18. In: Wikipedia. https://en.wikipedia.org/wiki/CCL18
  3. Chemokine CCL18. In: Wikidata. https://www.wikidata.org/wiki/Q21113934