Chemicals and Drugs

Cerulenin

An epoxydodecadienamide isolated from several species, including ACREMONIUM, Acrocylindrum, and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An epoxydodecadienamide isolated from several species, including ACREMONIUM, Acrocylindrum, and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function.

Chemical Identity

Chemical Information

Molecular Formula
C12H17NO3
Molecular Weight
223.27 g/mol
CAS Registry No.
17397-89-6
IUPAC Name
(2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboxamide
InChIKey
GVEZIHKRYBHEFX-NQQPLRFYSA-N
SMILES
C/C=C/C/C=C/CCC(=O)[C@@H]1[C@@H](O1)C(=O)N
MeSH Unique ID
D002569
Source
PubChem CID 5282054

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • 2,3-Epoxy-4-oxo-7,10-dodecadienoylamide

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not confuse with CERULEIN see CERULETIDE

MeSH Record

History Note

91(75); was see under ANTIBIOTICS, ANTIFUNGAL 1975-90

MeSH Record

Previous Indexing

  • Antibiotics, Antifungal (1973-1974)
  • Ethers, Cyclic (1973-1974)
  • Fatty Acids, Unsaturated (1974)

MeSH Hierarchy

Tree Number

  1. D02w.065w.327w

AMA Style

References

  1. National Library of Medicine. Cerulenin. Medical Subject Headings (MeSH). 2026. Unique ID D002569. http://id.nlm.nih.gov/mesh/2026/D002569
  2. Cerulenin. In: Wikipedia. https://en.wikipedia.org/wiki/Cerulenin
  3. Cerulenin. In: Wikidata. https://www.wikidata.org/wiki/Q5065296
  4. Cerulenin. In: PubChem Compound. CID 5282054. https://pubchem.ncbi.nlm.nih.gov/compound/5282054