Structured Summary
Abstract
An enzyme that catalyzes the hydrolysis of cerebroside 3-sulfate (sulfatide) to yield a cerebroside and inorganic sulfate. A marked deficiency of arylsulfatase A, which is considered the heat-labile component of cerebroside sulfatase, has been demonstrated in all forms of metachromatic leukodystrophy (LEUKODYSTROPHY, METACHROMATIC). EC 3.1.6.8.
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Synonyms
4 entry terms
- Arylsulfatase A
- Sulfatidate Sulfatase
- Cerebroside Sulfatase
- Sulfatase, Sulfatidate
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Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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Indexing Annotation
/defic: consider also LEUKODYSTROPHY, METACHROMATIC
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History Note
87(76); was see under SULFATASES 1976-86
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Previous Indexing
- Arylsulfatases (1975)
- Sulfatases (1972-1974)
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AMA Style
References
- National Library of Medicine. Cerebroside-Sulfatase. Medical Subject Headings (MeSH). 2026. Unique ID D002553. http://id.nlm.nih.gov/mesh/2026/D002553
- Cerebroside-Sulfatase. In: Wikipedia. https://en.wikipedia.org/wiki/Cerebroside-sulfatase
- Cerebroside-Sulfatase. In: Wikidata. https://www.wikidata.org/wiki/Q10762609