Chemicals and Drugs

Celecoxib

A pyrazole derivative and selective CYCLOOXYGENASE 2 INHIBITOR that is used to treat symptoms associated with RHEUMATOID ARTHRITIS; OSTEOARTHRITIS and JUVENILE ARTHRITIS, as well as the management of ACUTE PAIN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A pyrazole derivative and selective CYCLOOXYGENASE 2 INHIBITOR that is used to treat symptoms associated with RHEUMATOID ARTHRITIS; OSTEOARTHRITIS and JUVENILE ARTHRITIS, as well as the management of ACUTE PAIN.

Chemical Identity

Chemical Information

Molecular Formula
C17H14F3N3O2S
Molecular Weight
381.4 g/mol
CAS Registry No.
169590-42-5
IUPAC Name
4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
InChIKey
RZEKVGVHFLEQIL-UHFFFAOYSA-N
SMILES
CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F
MeSH Unique ID
D000068579
Source
PubChem CID 2662

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • 4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
  • Celebrex
  • SC 58635
  • SC-58635
  • SC58635

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (1997)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Celecoxib. Medical Subject Headings (MeSH). 2026. Unique ID D000068579. http://id.nlm.nih.gov/mesh/2026/D000068579
  2. Celecoxib. In: Wikipedia. https://en.wikipedia.org/wiki/Celecoxib
  3. Celecoxib. In: Wikidata. https://www.wikidata.org/wiki/Q408801
  4. Celecoxib. In: PubChem Compound. CID 2662. https://pubchem.ncbi.nlm.nih.gov/compound/2662