Structured Summary
Abstract
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
Chemical Identity
Chemical Information
- Molecular Formula
- C16H16N4O8S
- Molecular Weight
- 424.4 g/mol
- CAS Registry No.
- 55268-75-2
- IUPAC Name
- (6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- InChIKey
- JFPVXVDWJQMJEE-IZRZKJBUSA-N
- SMILES
- CO/N=C(/C1=CC=CO1)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)O
- MeSH Unique ID
- D002444
- Source
- PubChem CID 5479529
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
Drug Class
Pharmacological Action
MeSH Record
Synonyms
3 entry terms
- Cephuroxime
- Ketocef
- Zinacef
MeSH Record
Aspects Covered
26 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(80); was see under CEPHALOSPORINS 1980-90
MeSH Record
Previous Indexing
- Cephalosporins (1966-1979)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
QV 350.5.C3
AMA Style
References
- National Library of Medicine. Cefuroxime. Medical Subject Headings (MeSH). 2026. Unique ID D002444. http://id.nlm.nih.gov/mesh/2026/D002444
- Cefuroxime. In: Wikipedia. https://en.wikipedia.org/wiki/Cefuroxime
- Cefuroxime. In: Wikidata. https://www.wikidata.org/wiki/Q413728
- Cefuroxime. In: PubChem Compound. CID 5479529. https://pubchem.ncbi.nlm.nih.gov/compound/5479529