Chemicals and Drugs

Ceftriaxone

A broad-spectrum cephalosporin antibiotic and cefotaxime derivative with a very long half-life and high penetrability to meninges, eyes and inner ears.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A broad-spectrum cephalosporin antibiotic and cefotaxime derivative with a very long half-life and high penetrability to meninges, eyes and inner ears.

Chemical Identity

Chemical Information

Molecular Formula
C18H18N8O7S3
Molecular Weight
554.6 g/mol
CAS Registry No.
73384-59-5
IUPAC Name
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(2-methyl-5,6-dioxo-1H-1,2,4-triazin-3-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey
VAAUVRVFOQPIGI-SPQHTLEESA-N
SMILES
CN1C(=NC(=O)C(=O)N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)SC2)C(=O)O
MeSH Unique ID
D002443
Source
PubChem CID 5479530

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

31 entry terms
  • Cefatriaxone
  • Ceftriaxon
  • Benaxona
  • Cefaxona
  • Ceftrex
  • Ceftriaxon Curamed
  • Ceftriaxon Hexal
  • Ceftriaxona Andreu
  • Ceftriaxona LDP Torlan
  • Ceftriaxone Irex
  • Ceftriaxone Sodium
  • Ceftriaxone Sodium, Anhydrous
  • Ceftriaxone, Disodium Salt
  • Ceftriaxone, Disodium Salt, Hemiheptahydrate
  • Lendacin
  • Longacef
  • Longaceph
  • Ro 13-9904
  • Ro-13-9904
  • Ro13-9904
  • Rocefalin
  • Rocefin
  • Rocephin
  • Rocephine
  • Tacex
  • Terbac
  • Anhydrous Ceftriaxone Sodium
  • Ro 13 9904
  • Ro 139904
  • Ro13 9904
  • Ro139904

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1986

MeSH Record

Previous Indexing

  • Cefotaxime (1982-1985)
  • Cephalosporins (1966-1981)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.249w.190w.190w.155w
  2. D02w.886w.665w.074w.190w.190w.155w
  3. D03w.633.100.300w.249w.190w.190w.155w

MeSH Record

NLM Classification

QV 350.5.C3

AMA Style

References

  1. National Library of Medicine. Ceftriaxone. Medical Subject Headings (MeSH). 2026. Unique ID D002443. http://id.nlm.nih.gov/mesh/2026/D002443
  2. Ceftriaxone. In: Wikipedia. https://en.wikipedia.org/wiki/Ceftriaxone
  3. Ceftriaxone. In: Wikidata. https://www.wikidata.org/wiki/Q421713
  4. Ceftriaxone. In: PubChem Compound. CID 5479530. https://pubchem.ncbi.nlm.nih.gov/compound/5479530