Structured Summary
Abstract
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.
Chemical Identity
Chemical Information
- Molecular Formula
- C13H13N5O5S2
- Molecular Weight
- 383.4 g/mol
- CAS Registry No.
- 68401-81-0
- IUPAC Name
- (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- InChIKey
- NNULBSISHYWZJU-LLKWHZGFSA-N
- SMILES
- CO/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=CCS3)C(=O)O
- MeSH Unique ID
- D015296
- Source
- PubChem CID 6533629
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
18 entry terms
- Cefizox
- Ceftizoxime Monosodium Salt
- Ceftizoxime Sodium
- FK-749
- FK749
- FR-13749
- SK&F 88373-2
- SKF-88373
- FK 749
- FR 13749
- FR13749
- Monosodium Salt, Ceftizoxime
- SK&F 88373 2
- SK&F 883732
- SKF 88373
- SKF88373
- Salt, Ceftizoxime Monosodium
- Sodium, Ceftizoxime
MeSH Record
Aspects Covered
26 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
89
MeSH Record
Previous Indexing
- Cefotaxime/analogs & derivatives (1982-1988)
- Cephalosporins (1979-1981)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Ceftizoxime. Medical Subject Headings (MeSH). 2026. Unique ID D015296. http://id.nlm.nih.gov/mesh/2026/D015296
- Ceftizoxime. In: Wikipedia. https://en.wikipedia.org/wiki/Ceftizoxime
- Ceftizoxime. In: Wikidata. https://www.wikidata.org/wiki/Q1082945
- Ceftizoxime. In: PubChem Compound. CID 6533629. https://pubchem.ncbi.nlm.nih.gov/compound/6533629