Chemicals and Drugs

Ceftaroline

A fifth-generation cephalosporin antibacterial agent that is used to treat skin infections caused by bacteria in adults and newborns. Ceftaroline has a 1,3-thiazolidine ring attached to the C-7 position of its cephalosporin core.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A fifth-generation cephalosporin antibacterial agent that is used to treat skin infections caused by bacteria in adults and newborns. Ceftaroline has a 1,3-thiazolidine ring attached to the C-7 position of its cephalosporin core.

Chemical Identity

Chemical Information

Molecular Formula
C22H20N8O5S4
Molecular Weight
604.7 g/mol
CAS Registry No.
189345-04-8
IUPAC Name
(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-ethoxyiminoacetyl]amino]-3-[[4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
InChIKey
RGFBRLNVZCCMSV-BIRGHMBHSA-N
SMILES
CCO/N=C(/C1=NSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)SC4=NC(=CS4)C5=CC=[N+](C=C5)C)C(=O)[O-]
MeSH Unique ID
D000097583
Source
PubChem CID 9938701

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • Ceftaroline Fosamil
  • PPI-0903
  • PPI0903
  • T 91825
  • T-91825
  • T91825
  • TAK-599
  • TAK599
  • Teflaro
  • Zinforo
  • 91825, T
  • Fosamil, Ceftaroline
  • PPI 0903
  • TAK 599

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2024 (2004)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.249w.186
  2. D02w.886w.665w.074w.186
  3. D03w.633.100.300w.249w.186

AMA Style

References

  1. National Library of Medicine. Ceftaroline. Medical Subject Headings (MeSH). 2026. Unique ID D000097583. http://id.nlm.nih.gov/mesh/2026/D000097583
  2. Ceftaroline. In: Wikidata. https://www.wikidata.org/wiki/Q27139048
  3. Ceftaroline. In: PubChem Compound. CID 9938701. https://pubchem.ncbi.nlm.nih.gov/compound/9938701