Chemicals and Drugs

Cefpirome

A fourth-generation cephalosporin antibacterial agent. Appears to be more active in vitro against Staphylococci, some Enterococci, some ENTEROBACTERIACEAE, and PSEUDOMONAS AERUGINOSA.Cefpirome has a pyridinium group attached to C-3 position of its cephalosporin core.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A fourth-generation cephalosporin antibacterial agent. Appears to be more active in vitro against Staphylococci, some Enterococci, some ENTEROBACTERIACEAE, and PSEUDOMONAS AERUGINOSA.Cefpirome has a pyridinium group attached to C-3 position of its cephalosporin core.

Chemical Identity

Chemical Information

Molecular Formula
C22H22N6O5S2
Molecular Weight
514.6 g/mol
CAS Registry No.
84957-29-9
IUPAC Name
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(6,7-dihydro-5H-cyclopenta[b]pyridin-1-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
InChIKey
DKOQGJHPHLTOJR-WHRDSVKCSA-N
SMILES
CO/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4=CC=CC5=C4CCC5)C(=O)[O-]
MeSH Unique ID
D000097572
Source
PubChem CID 5479539

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • 3-((2,3-cyclopenteno-1-pyridinium)methyl)-7-(2-syn-methoximino-2-(2-aminothiazole-4-yl)acetamido)ceph-3-em-4-carboxylate
  • Cefpirome Sulfate
  • Cefrom
  • HR 810
  • HR-810
  • 810, HR
  • Sulfate, Cefpirome

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2024 (1983)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.249w.181w
  2. D02w.886w.665w.074w.181w
  3. D03w.633.100.300w.249w.181w

AMA Style

References

  1. National Library of Medicine. Cefpirome. Medical Subject Headings (MeSH). 2026. Unique ID D000097572. http://id.nlm.nih.gov/mesh/2026/D000097572
  2. Cefpirome. In: Wikipedia. https://en.wikipedia.org/wiki/Cefpirome
  3. Cefpirome. In: Wikidata. https://www.wikidata.org/wiki/Q2943814
  4. Cefpirome. In: PubChem Compound. CID 5479539. https://pubchem.ncbi.nlm.nih.gov/compound/5479539