Chemicals and Drugs

Cefotiam

One of the CEPHALOSPORINS that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

One of the CEPHALOSPORINS that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.

Chemical Identity

Chemical Information

Molecular Formula
C18H23N9O4S3
Molecular Weight
525.6 g/mol
CAS Registry No.
61622-34-2
IUPAC Name
(6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-[2-(dimethylamino)ethyl]tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey
QYQDKDWGWDOFFU-IUODEOHRSA-N
SMILES
CN(C)CCN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)CC4=CSC(=N4)N)SC2)C(=O)O
MeSH Unique ID
D015310
Source
PubChem CID 43708

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • Abbott-48999
  • CGP-14221-E
  • Cefotiam Hydrochloride
  • Ceradolan
  • Haloapor
  • Halospor
  • SCE-963
  • Abbott 48999
  • Abbott48999
  • CGP 14221 E
  • CGP14221E
  • Hydrochloride, Cefotiam
  • SCE 963
  • SCE963

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

89

MeSH Record

Previous Indexing

  • Cefotaxime/analogs & derivatives (1982-1988)
  • Cephalosporins (1979-1981)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.249w.190w.190w.135w
  2. D02w.886w.665w.074w.190w.190w.135w
  3. D03w.633.100.300w.249w.190w.190w.135w

AMA Style

References

  1. National Library of Medicine. Cefotiam. Medical Subject Headings (MeSH). 2026. Unique ID D015310. http://id.nlm.nih.gov/mesh/2026/D015310
  2. Cefotiam. In: Wikipedia. https://en.wikipedia.org/wiki/Cefotiam
  3. Cefotiam. In: Wikidata. https://www.wikidata.org/wiki/Q3009984
  4. Cefotiam. In: PubChem Compound. CID 43708. https://pubchem.ncbi.nlm.nih.gov/compound/43708