Chemicals and Drugs

Cefoperazone

Semisynthetic broad-spectrum cephalosporin with a tetrazolyl moiety that is resistant to beta-lactamase. It may be used to treat Pseudomonas infections.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Semisynthetic broad-spectrum cephalosporin with a tetrazolyl moiety that is resistant to beta-lactamase. It may be used to treat Pseudomonas infections.

Chemical Identity

Chemical Information

Molecular Formula
C25H27N9O8S2
Molecular Weight
645.7 g/mol
CAS Registry No.
62893-19-0
IUPAC Name
(6R,7R)-7-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey
GCFBRXLSHGKWDP-XCGNWRKASA-N
SMILES
CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O
MeSH Unique ID
D002438
Source
PubChem CID 44187

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Cefoperazon
  • Cefobid
  • Cefoperazone Sodium
  • Cefoperazone Sodium Salt
  • Céfobis
  • T-1551
  • T1551
  • Salt, Cefoperazone Sodium
  • Sodium Salt, Cefoperazone
  • Sodium, Cefoperazone
  • T 1551

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

84

MeSH Record

Previous Indexing

  • Cephalosporins (1966-1983)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.249w.150w.160w
  2. D02w.886w.665w.074w.150w.160w
  3. D03w.633.100.300w.249w.150w.160w

AMA Style

References

  1. National Library of Medicine. Cefoperazone. Medical Subject Headings (MeSH). 2026. Unique ID D002438. http://id.nlm.nih.gov/mesh/2026/D002438
  2. Cefoperazone. In: Wikipedia. https://en.wikipedia.org/wiki/Cefoperazone
  3. Cefoperazone. In: Wikidata. https://www.wikidata.org/wiki/Q2325775
  4. Cefoperazone. In: PubChem Compound. CID 44187. https://pubchem.ncbi.nlm.nih.gov/compound/44187