Chemicals and Drugs

Cefixime

A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.

Chemical Identity

Chemical Information

Molecular Formula
C16H15N5O7S2
Molecular Weight
453.5 g/mol
CAS Registry No.
79350-37-1
IUPAC Name
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey
OKBVVJOGVLARMR-QSWIMTSFSA-N
SMILES
C=CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OCC(=O)O)/C3=CSC(=N3)N)SC1)C(=O)O
MeSH Unique ID
D020682
Source
PubChem CID 5362065

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • Cefixime Anhydrous
  • Cefixime Trihydrate
  • FK 027
  • FK-027
  • FR-17027
  • Suprax
  • FK027
  • FR 17027
  • FR17027

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2000 (1984)

MeSH Record

Previous Indexing

  • Cefotaxime/analogs & derivatives (1986-1999)
  • Cephalosporins (1984-1985)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Cefixime. Medical Subject Headings (MeSH). 2026. Unique ID D020682. http://id.nlm.nih.gov/mesh/2026/D020682
  2. Cefixime. In: Wikipedia. https://en.wikipedia.org/wiki/Cefixime
  3. Cefixime. In: Wikidata. https://www.wikidata.org/wiki/Q163901
  4. Cefixime. In: PubChem Compound. CID 5362065. https://pubchem.ncbi.nlm.nih.gov/compound/5362065