Chemicals and Drugs

Cdc20 Proteins

Highly conserved proteins that specifically bind to and activate the anaphase-promoting complex-cyclosome, promoting ubiquitination and proteolysis of cell-cycle-regulatory proteins. Cdc20 is essential for anaphase-promoting complex activity, initiation of anaphase, and cyclin proteolysis during mitosis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Highly conserved proteins that specifically bind to and activate the anaphase-promoting complex-cyclosome, promoting ubiquitination and proteolysis of cell-cycle-regulatory proteins. Cdc20 is essential for anaphase-promoting complex activity, initiation of anaphase, and cyclin proteolysis during mitosis.

MeSH Record

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MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2014

MeSH Record

Previous Indexing

  • Cell Cycle Proteins (1987-2013)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.464w.938.750.092.998
  2. D12.776w.167.024.998

AMA Style

References

  1. National Library of Medicine. Cdc20 Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D064199. http://id.nlm.nih.gov/mesh/2026/D064199
  2. Cdc20 Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q21422912