Chemicals and Drugs

Cathepsin K

A cysteine protease that is highly expressed in OSTEOCLASTS and plays an essential role in BONE RESORPTION as a potent EXTRACELLULAR MATRIX-degrading enzyme.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cysteine protease that is highly expressed in OSTEOCLASTS and plays an essential role in BONE RESORPTION as a potent EXTRACELLULAR MATRIX-degrading enzyme.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

Cathepsin X, an obsolete multi-meaning term appearing in older literature goes here or at CATHEPSIN Z: check text; Cathepsin O and Cathepsin O2 in older literature go here.

MeSH Record

History Note

2010(1984)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.656w.224w.405
  2. D08.811w.277w.656w.262w.500.156
  3. D08.811w.277w.656w.300w.200.156

AMA Style

References

  1. National Library of Medicine. Cathepsin K. Medical Subject Headings (MeSH). 2026. Unique ID D056657. http://id.nlm.nih.gov/mesh/2026/D056657
  2. Cathepsin K. In: Wikidata. https://www.wikidata.org/wiki/Q22679008