Chemicals and Drugs

Cathepsin D

An intracellular proteinase found in a variety of tissue. It has specificity similar to but narrower than that of pepsin A. The enzyme is involved in catabolism of cartilage and connective tissue. EC 3.4.23.5. (Formerly EC 3.4.4.23).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An intracellular proteinase found in a variety of tissue. It has specificity similar to but narrower than that of pepsin A. The enzyme is involved in catabolism of cartilage and connective tissue. EC 3.4.23.5. (Formerly EC 3.4.4.23).

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

85

MeSH Record

Previous Indexing

  • Cathepsins (1966-1984)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.656w.074w.500.180
  2. D08.811w.277w.656w.224w.187
  3. D08.811w.277w.656w.300w.048.180

AMA Style

References

  1. National Library of Medicine. Cathepsin D. Medical Subject Headings (MeSH). 2026. Unique ID D002402. http://id.nlm.nih.gov/mesh/2026/D002402
  2. Cathepsin D. In: Wikidata. https://www.wikidata.org/wiki/Q21157699