Chemicals and Drugs

Caspase 3

A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

7 entry terms
  • Apopain
  • CASP3
  • Caspase-3
  • Pro-Caspase-3
  • Procaspase-3
  • Pro Caspase 3
  • Procaspase 3

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(1995)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.656w.262w.500.126w.350.300
  2. D08.811w.277w.656w.300w.200.126w.350.300
  3. D12.776w.476.075.405w.350.300

AMA Style

References

  1. National Library of Medicine. Caspase 3. Medical Subject Headings (MeSH). 2026. Unique ID D053148. http://id.nlm.nih.gov/mesh/2026/D053148
  2. Caspase 3. In: Wikidata. https://www.wikidata.org/wiki/Q5049057