Chemicals and Drugs

Carbamoyl-Phosphate Synthase (Ammonia)

An enzyme that catalyzes the formation of carbamoyl phosphate from ATP, carbon dioxide, and ammonia. This enzyme is specific for arginine biosynthesis or the urea cycle. Absence or lack of this enzyme may cause CARBAMOYL-PHOSPHATE SYNTHASE I DEFICIENCY DISEASE. EC 6.3.4.16.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the formation of carbamoyl phosphate from ATP, carbon dioxide, and ammonia. This enzyme is specific for arginine biosynthesis or the urea cycle. Absence or lack of this enzyme may cause CARBAMOYL-PHOSPHATE SYNTHASE I DEFICIENCY DISEASE. EC 6.3.4.16.

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Classification

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See Also

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Synonyms

10 entry terms
  • CP Synthase I
  • Carbamoyl Phosphate Synthetase I
  • Carbamoyl-Phosphate Synthetase (Ammonia)
  • Carbamoyl-Phosphate Synthetase I
  • Carbamoylphosphate Synthetase I
  • Carbamyl Phosphate Synthase (Ammonia)
  • Carbamyl-Phosphate Synthase (Ammonia)
  • Synthase I, CP
  • Synthetase I, Carbamoyl-Phosphate
  • Synthetase I, Carbamoylphosphate

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/defic: consider CARBAMOYL-PHOSPHATE SYNTHETASE I DEFICIENCY DISEASE

MeSH Record

History Note

98(75)

MeSH Record

Previous Indexing

  • Ammonia (1974)
  • Carbamates (1974)
  • Phosphotransferases, ATP (1974)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Carbamoyl-Phosphate Synthase (Ammonia). Medical Subject Headings (MeSH). 2026. Unique ID D002222. http://id.nlm.nih.gov/mesh/2026/D002222
  2. Carbamoyl-Phosphate Synthase (Ammonia). In: Wikidata. https://www.wikidata.org/wiki/Q24772854