Capreomycin

Cyclic peptide antibiotic similar to VIOMYCIN. It is produced by Streptomyces capreolus.

Molecular Formula

C₅₀H₈₈N₂₈O₁₅

Molecular Weight

1321.4 g/mol

IUPAC Name

(3S)-3,6-diamino-N-[[(2S,5S,8E,11S,15S)-15-amino-11-[(4R)-2-amino-1,4,5,6-tetrahydropyrimidin-4-yl]-8-[(carbamoylamino)methylidene]-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]hexanamide;(3S)-3,6-diamino-N-[[(2S,5S,8E,11S,15S)-15-amino-11-[(4R)-2-amino-1,4,5,6-tetrahydropyrimidin-4-yl]-8-[(carbamoylamino)methylidene]-2-methyl-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]hexanamide

InChIKey

VCOPTHOUUNAYKQ-WBTCAYNUSA-N

SMILES

C[C@H]1C(=O)N[C@H](C(=O)N/C(=C/NC(=O)N)/C(=O)N[C@H](C(=O)NC[C@@H](C(=O)N1)N)[C@H]2CCNC(=N2)N)CNC(=O)C[C@H](CCCN)N.C1CNC(=N[C@H]1[C@H]2C(=O)NC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N/C(=C/NC(=O)N)/C(=O)N2)CNC(=O)C[C@H](CCCN)N)CO)N)N

MeSH Unique ID

D002207

Source

PubChem CID 135483770

• Anti-Bacterial Agents
• Antitubercular Antibiotics
• Protein Synthesis Inhibitors

2009(1996)

• Antitubercular Agents (1966-1971)

1. D04w.345w.566w.142w
2. D12.644w.641w.142w

1. National Library of Medicine. Capreomycin. Medical Subject Headings (MeSH). 2026. Unique ID D002207. http://id.nlm.nih.gov/mesh/2026/D002207
2. Capreomycin. In: Wikipedia. https://en.wikipedia.org/wiki/Capreomycin
3. Capreomycin. In: Wikidata. https://www.wikidata.org/wiki/Q415909
4. Capreomycin. In: PubChem Compound. CID 135483770. https://pubchem.ncbi.nlm.nih.gov/compound/135483770