Chemicals and Drugs

Calcium-Sensing Receptors

A class of G-protein-coupled receptors that react to varying extracellular CALCIUM levels. Calcium-sensing receptors in the PARATHYROID GLANDS play an important role in the maintenance of calcium HOMEOSTASIS by regulating the release of PARATHYROID HORMONE. They differ from INTRACELLULAR CALCIUM-SENSING PROTEINS which sense intracellular calcium levels.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A class of G-protein-coupled receptors that react to varying extracellular CALCIUM levels. Calcium-sensing receptors in the PARATHYROID GLANDS play an important role in the maintenance of calcium HOMEOSTASIS by regulating the release of PARATHYROID HORMONE. They differ from INTRACELLULAR CALCIUM-SENSING PROTEINS which sense intracellular calcium levels.

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Classification

Broader headings

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Synonyms

27 entry terms
  • CASR Protein
  • Ca-Sensing Receptors
  • Ca2+-Sensing Receptor
  • Calcium Receptors
  • Calcium-Sensing Receptor
  • Calcium-Sensing Receptor Protein
  • Extracellular Calcium-Ion Sensing Receptor
  • Receptor, Ca-Sensing
  • Receptors, Calcium
  • Receptors, Calcium-Sensing
  • Ca Sensing Receptors
  • Ca-Sensing Receptor
  • Ca2+ Sensing Receptor
  • Calcium Sensing Receptor
  • Calcium Sensing Receptor Protein
  • Calcium Sensing Receptors
  • Extracellular Calcium Ion Sensing Receptor
  • Receptor Protein, Calcium-Sensing
  • Receptor, Ca Sensing
  • Receptor, Ca2+-Sensing
  • Receptor, Calcium-Sensing
  • Receptors, Ca-Sensing
  • Receptors, Calcium Sensing
  • Parathyroid Calcium-Sensing Receptor
  • Calcium-Sensing Receptor, Parathyroid
  • Parathyroid Calcium Sensing Receptor
  • Receptor, Parathyroid Calcium-Sensing

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

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Indexing Annotation

CALCIUM-BINDING PROTEINS is also available

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History Note

2004; CALCIUM-SENSING RECEPTOR (now RECEPTORS, CALCIUM-SENSING) was indexed under RECEPTORS, CELL SURFACE; for CALCIUM RECEPTORS use CALCIUM-BINDING PROTEINS 1982-2003; for RECEPTORS, CALCIUM use CALCIUM-BINDING PROTEINS 1996-2003

MeSH Record

Previous Indexing

  • Receptors, Cell Surface (1994-2003)

MeSH Hierarchy

Tree Number

  1. D12.776w.543w.750w.695w.115w

AMA Style

References

  1. National Library of Medicine. Calcium-Sensing Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D044169. http://id.nlm.nih.gov/mesh/2026/D044169
  2. Calcium-Sensing Receptors. In: Wikipedia. https://en.wikipedia.org/wiki/Calcium-sensing_receptor
  3. Calcium-Sensing Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q417801