Chemicals and Drugs

Calcitonin Gene-Related Peptide

A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.

MeSH Record

Classification

Broader headings

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Drug Class

Pharmacological Action

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MeSH Record

Synonyms

12 entry terms
  • Calcitonin Gene Related Peptide
  • Gene-Related Peptide, Calcitonin
  • Calcitonin Gene-Related Peptide I
  • Calcitonin Gene-Related Peptide II
  • alpha-CGRP
  • alpha-Calcitonin Gene-Related Peptide
  • beta-CGRP
  • beta-Calcitonin Gene-Related Peptide
  • Calcitonin Gene Related Peptide I
  • Calcitonin Gene Related Peptide II
  • alpha Calcitonin Gene Related Peptide
  • beta Calcitonin Gene Related Peptide

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1990

MeSH Record

Previous Indexing

  • Nerve Tissue Proteins (1966-1986)
  • Neuropeptides (1987-1989)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Calcitonin Gene-Related Peptide. Medical Subject Headings (MeSH). 2026. Unique ID D015740. http://id.nlm.nih.gov/mesh/2026/D015740
  2. Calcitonin Gene-Related Peptide. In: Wikidata. https://www.wikidata.org/wiki/Q24725687