Chemicals and Drugs

Cadherins

Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

32 entry terms
  • Cadherin
  • Cadherin-1
  • Cadherin-2
  • Cadherin-3
  • E-Cadherin
  • E-Cadherins
  • Epithelial-Cadherin
  • Epithelial-Cadherins
  • Liver Cell Adhesion Molecule
  • Liver Cell Adhesion Molecules
  • N-Cadherin
  • N-Cadherins
  • Neural Cadherin
  • Neural Cadherins
  • P-Cadherin
  • P-Cadherins
  • Placental Cadherins
  • Uvomorulin
  • Cadherin 1
  • Cadherin 2
  • Cadherin 3
  • Cadherin, Neural
  • Cadherins, Neural
  • Cadherins, Placental
  • E Cadherin
  • E Cadherins
  • Epithelial Cadherin
  • Epithelial Cadherins
  • N Cadherin
  • N Cadherins
  • P Cadherin
  • P Cadherins

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

90; N CADHERIN was NM 1994-95; LIVER CELL ADHESION MOLECULES was see CELL ADHESION MOLECULES 1990-95

MeSH Record

Previous Indexing

  • Antigens, Surface (1979-1989)
  • Calcium-Binding Proteins (1980-1989)
  • Glycoproteins (1966-1987)
  • Membrane Glycoproteins (1988-1989)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Cadherins. Medical Subject Headings (MeSH). 2026. Unique ID D015820. http://id.nlm.nih.gov/mesh/2026/D015820
  2. Cadherins. In: Wikipedia. https://en.wikipedia.org/wiki/Cadherin
  3. Cadherins. In: Wikidata. https://www.wikidata.org/wiki/Q24776048