Structured Summary
Abstract
A member of the CELF PROTEINS family which binds GU rich elements (GREs) and CUG-triplet repeats in the 3'UTR of mammalian mRNA transcripts that undergo rapid turnover. It also binds AU-rich elements (AREs or EDEN-like) in the 3'UTR of JUN and FOS mRNAs. Mutations in the human CELF1 gene are associated with MYOTONIC DYSTROPHY type 1.
MeSH Record
Classification
Broader headings
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MeSH Record
Synonyms
13 entry terms
- BRUNOL2 Protein
- Bruno-Like 2 Protein
- CUG Triplet Repeat, RNA-Binding Protein 1
- CUGBP, Elav-Like Family Member 1 Protein
- CUGBP1 Protein
- 2 Protein, Bruno-Like
- Bruno Like 2 Protein
- CUG Triplet Repeat, RNA Binding Protein 1
- CUGBP, Elav Like Family Member 1 Protein
- Protein, BRUNOL2
- Protein, Bruno-Like 2
- Protein, CELF1
- Protein, CUGBP1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2016
MeSH Record
Previous Indexing
- RNA-Binding Proteins (2005-2015)
- Ribonucleoproteins (1997-2004)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. CELF1 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D000067879. http://id.nlm.nih.gov/mesh/2026/D000067879
- CELF1 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21117196