Chemicals and Drugs

CD58 Antigens

Glycoproteins with a wide distribution on hematopoietic and non-hematopoietic cells and strongly expressed on MACROPHAGES. CD58 mediates cell adhesion by binding to CD2; (CD2 ANTIGENS); and this enhances antigen-specific T-cell activation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Glycoproteins with a wide distribution on hematopoietic and non-hematopoietic cells and strongly expressed on MACROPHAGES. CD58 mediates cell adhesion by binding to CD2; (CD2 ANTIGENS); and this enhances antigen-specific T-cell activation.

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Synonyms

6 entry terms
  • Antigens, CD58
  • CD58 Antigen
  • LFA-3
  • Lymphocyte Function Associated Antigen-3
  • Antigen, CD58
  • Lymphocyte Function Associated Antigen 3

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

differentiation antigens

MeSH Record

History Note

2018 (1988); use LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN-3 1988-95

MeSH Record

Previous Indexing

  • Antigens, CD (1990-1995)
  • Antigens, Differentiation (1990-1991)
  • Antigens, Surface (1988-1992)
  • Membrane Glycoproteins (1988-1995)

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References

  1. National Library of Medicine. CD58 Antigens. Medical Subject Headings (MeSH). 2026. Unique ID D018968. http://id.nlm.nih.gov/mesh/2026/D018968
  2. CD58 Antigens. In: Wikipedia. https://en.wikipedia.org/wiki/CD58
  3. CD58 Antigens. In: Wikidata. https://www.wikidata.org/wiki/Q21113587