Diseases

CADASIL

A familial, cerebral arteriopathy mapped to chromosome 19q12, and characterized by the presence of granular deposits in small CEREBRAL ARTERIES producing ischemic STROKE; PSEUDOBULBAR PALSY; and multiple subcortical infarcts (CEREBRAL INFARCTION). CADASIL is an acronym for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. CADASIL differs from BINSWANGER DISEASE by the presence of MIGRAINE WITH AURA and usually by the lack of history of arterial HYPERTENSION. (From Bradley et al, Neurology in Clinical Practice, 2000, p1146)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A familial, cerebral arteriopathy mapped to chromosome 19q12, and characterized by the presence of granular deposits in small CEREBRAL ARTERIES producing ischemic STROKE; PSEUDOBULBAR PALSY; and multiple subcortical infarcts (CEREBRAL INFARCTION). CADASIL is an acronym for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. CADASIL differs from BINSWANGER DISEASE by the presence of MIGRAINE WITH AURA and usually by the lack of history of arterial HYPERTENSION. (From Bradley et al, Neurology in Clinical Practice, 2000, p1146)

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • Cerebral Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
  • Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
  • Dementia, Hereditary Multi-Infarct Type
  • Dementia, Hereditary Multi Infarct Type
  • CADASILM

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2005; use DEMENTIA, MULTI-INFARCT 2000-2004

MeSH Record

Previous Indexing

  • Cerebrovascular Disorders (1994-2004)
  • Dementia, Multi-Infarct (1994-2004)

MeSH Hierarchy

Tree Numbers

  1. C10w.228w.140w.300w.150w.477.200w.100w
  2. C10w.228w.140w.300w.275.249w
  3. C10w.228w.140w.300w.400w.203w
  4. C10w.228w.140w.300w.510.200.175w
  5. C10w.228w.140w.300w.775w.200.200w.100w
  6. C10w.228w.140w.380w.230w.124w
  7. C14w.907w.253w.092w.477.200w.100w
  8. C14w.907w.253w.329.249w
  9. C14w.907w.253w.560.200.175w
  10. C14w.907w.253w.855w.200.200w.100w
  11. C16w.320w.129w
  12. C23.550.513w.355w.250.200w.100w
  13. C23.550.717w.489w.250.200w.100w

AMA Style

References

  1. National Library of Medicine. CADASIL. Medical Subject Headings (MeSH). 2026. Unique ID D046589. http://id.nlm.nih.gov/mesh/2026/D046589
  2. CADASIL. In: Wikipedia. https://en.wikipedia.org/wiki/CADASIL
  3. CADASIL. In: Wikidata. https://www.wikidata.org/wiki/Q1022718