Chemicals and Drugs

Bupropion

A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.

Chemical Identity

Chemical Information

Molecular Formula
C13H18ClNO
Molecular Weight
239.74 g/mol
CAS Registry No.
34911-55-2
IUPAC Name
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
InChIKey
SNPPWIUOZRMYNY-UHFFFAOYSA-N
SMILES
CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C
MeSH Unique ID
D016642
Source
PubChem CID 444

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

10 entry terms
  • (+-)-1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
  • Amfebutamone
  • Bupropion Hydrochloride
  • Bupropion Hydrochloride, (+-)-Isomer
  • Bupropion, (+-)-Isomer
  • Quomen
  • Wellbutrin
  • Zyban (Anti-Smoking)
  • Zyban (Bupropion)
  • Zyntabac

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1992 (1978)

MeSH Record

Previous Indexing

  • Antidepressive Agents (1966-1991)
  • Propiophenones (1966-1991)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Bupropion. Medical Subject Headings (MeSH). 2026. Unique ID D016642. http://id.nlm.nih.gov/mesh/2026/D016642
  2. Bupropion. In: Wikipedia. https://en.wikipedia.org/wiki/Bupropion
  3. Bupropion. In: Wikidata. https://www.wikidata.org/wiki/Q834280
  4. Bupropion. In: PubChem Compound. CID 444. https://pubchem.ncbi.nlm.nih.gov/compound/444