Chemicals and Drugs

Bucladesine

A cyclic nucleotide derivative that mimics the action of endogenous CYCLIC AMP and is capable of permeating the cell membrane. It has vasodilator properties and is used as a cardiac stimulant. (From Merck Index, 11th ed)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cyclic nucleotide derivative that mimics the action of endogenous CYCLIC AMP and is capable of permeating the cell membrane. It has vasodilator properties and is used as a cardiac stimulant. (From Merck Index, 11th ed)

Chemical Identity

Chemical Information

Molecular Formula
C18H24N5O8P
Molecular Weight
469.4 g/mol
CAS Registry No.
362-74-3
IUPAC Name
[(4aR,6R,7R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl] butanoate
InChIKey
CJGYSWNGNKCJSB-YVLZZHOMSA-N
SMILES
CCCC(=O)NC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@H]4[C@H](O3)COP(=O)(O4)O)OC(=O)CCC
MeSH Unique ID
D003994
Source
PubChem CID 9687

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

19 entry terms
  • (But)(2) cAMP
  • DBcAMP
  • Dibutyryl Adenosine 3,5 Monophosphate
  • Dibutyryl Adenosine-3',5'-Monophosphate
  • Dibutyryl Cyclic AMP
  • N',O'-Dibutyryl-cAMP
  • N(6),0(2')-Dibutyryl Cyclic AMP
  • AMP, Dibutyryl Cyclic
  • Adenosine-3',5'-Monophosphate, Dibutyryl
  • Cyclic AMP, Dibutyryl
  • Dibutyryl Adenosine 3',5' Monophosphate
  • N',O' Dibutyryl cAMP
  • Bucladesine, Barium (1:1) Salt
  • Bucladesine, Disodium Salt
  • Bucladesine, Monosodium Salt
  • Bucladesine, Sodium Salt
  • Disodium Salt Bucladesine
  • Monosodium Salt Bucladesine
  • Sodium Salt Bucladesine

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

94; was DIBUTYRYL CYCLIC AMP 1974-93

MeSH Hierarchy

Tree Numbers

  1. D03w.633.100.759.646.138.395w.250w
  2. D13.695w.462w.200w.250w
  3. D13.695w.667.138.395w.250w
  4. D13.695w.827w.068.395w.250w

AMA Style

References

  1. National Library of Medicine. Bucladesine. Medical Subject Headings (MeSH). 2026. Unique ID D003994. http://id.nlm.nih.gov/mesh/2026/D003994
  2. Bucladesine. In: Wikipedia. https://en.wikipedia.org/wiki/Bucladesine
  3. Bucladesine. In: Wikidata. https://www.wikidata.org/wiki/Q4983616
  4. Bucladesine. In: PubChem Compound. CID 9687. https://pubchem.ncbi.nlm.nih.gov/compound/9687