Chemicals and Drugs

Bromocriptine

A semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion.

Chemical Identity

Chemical Information

Molecular Formula
C32H40BrN5O5
Molecular Weight
654.6 g/mol
CAS Registry No.
25614-03-3
IUPAC Name
(6aR,9R)-5-bromo-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-propan-2-yl-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
InChIKey
OZVBMTJYIDMWIL-AYFBDAFISA-N
SMILES
CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C(C)C)NC(=O)[C@H]4CN([C@@H]5CC6=C(NC7=CC=CC(=C67)C5=C4)Br)C)O
MeSH Unique ID
D001971
Source
PubChem CID 31101

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

22 entry terms
  • 2-Bromo-alpha-ergocryptine
  • 2-Bromo-alpha-ergokryptine
  • 2-Bromoergocryptine
  • 2-Bromoergokryptine
  • Bromocriptin
  • Bromocryptin
  • 2 Bromo alpha ergocryptine
  • 2 Bromo alpha ergokryptine
  • 2 Bromoergocryptine
  • 2 Bromoergokryptine
  • 2-Bromoergocryptine Mesylate
  • 2-Bromoergocryptine Methanesulfonate
  • Bromocriptine Mesylate
  • CB-154
  • Parlodel
  • 2 Bromoergocryptine Mesylate
  • 2 Bromoergocryptine Methanesulfonate
  • CB 154
  • CB154
  • Mesylate, 2-Bromoergocryptine
  • Mesylate, Bromocriptine
  • Methanesulfonate, 2-Bromoergocryptine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

81; was 2-BROMOERGOCRYPTINE 1978-80, was 2-BROMOERGOCRYPTINE see under ERGOTOXINE 1977, was 2-BROMOERGOCRYPTINE see under ERGOLINES 1975-76

MeSH Record

Previous Indexing

  • Ergot Alkaloids (1966-1974)

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.327.412.100w
  2. D03w.633.400.439.131w
  3. D03w.633.400.562.100w

AMA Style

References

  1. National Library of Medicine. Bromocriptine. Medical Subject Headings (MeSH). 2026. Unique ID D001971. http://id.nlm.nih.gov/mesh/2026/D001971
  2. Bromocriptine. In: Wikipedia. https://en.wikipedia.org/wiki/Bromocriptine
  3. Bromocriptine. In: Wikidata. https://www.wikidata.org/wiki/Q413581
  4. Bromocriptine. In: PubChem Compound. CID 31101. https://pubchem.ncbi.nlm.nih.gov/compound/31101