Structured Summary
Abstract
A fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity.
Chemical Identity
Chemical Information
- Molecular Formula
- C16H24O4
- Molecular Weight
- 280.36 g/mol
- CAS Registry No.
- 20350-15-6
- IUPAC Name
- (1R,2R,3E,7S,11E,13S,15S)-2,15-dihydroxy-7-methyl-6-oxabicyclo[11.3.0]hexadeca-3,11-dien-5-one
- InChIKey
- KQNZDYYTLMIZCT-KQPMLPITSA-N
- SMILES
- C[C@H]1CCC/C=C/[C@@H]2C[C@@H](C[C@H]2[C@@H](/C=C/C(=O)O1)O)O
- MeSH Unique ID
- D020126
- Source
- PubChem CID 5287620
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
7 entry terms
- Ascotoxin
- Cyanein
- Decumbin
- Synergisidin
- NSC-89671
- NSC 89671
- NSC89671
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
1999; use BREFELDIN A (NM) 1980-1998
MeSH Record
Previous Indexing
- Cyclopentanes (1974-1998)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Brefeldin A. Medical Subject Headings (MeSH). 2026. Unique ID D020126. http://id.nlm.nih.gov/mesh/2026/D020126
- Brefeldin A. In: Wikipedia. https://en.wikipedia.org/wiki/Brefeldin_A
- Brefeldin A. In: Wikidata. https://www.wikidata.org/wiki/Q168790
- Brefeldin A. In: PubChem Compound. CID 5287620. https://pubchem.ncbi.nlm.nih.gov/compound/5287620