Structured Summary
Abstract
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
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Classification
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MeSH Record
Synonyms
5 entry terms
- Bone Turnover
- Bone Turnovers
- Remodeling, Bone
- Turnover, Bone
- Turnovers, Bone
MeSH Record
Aspects Covered
5 allowable subheadings
Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.
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Indexing Annotation
note category: an aspect of bone physiol
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History Note
92
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Previous Indexing
- Bone Development (1967-1991)
- Bone Regeneration (1967-1991)
- Bone Resorption (1967-1991)
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NLM Classification
WE 202
AMA Style
References
- National Library of Medicine. Bone Remodeling. Medical Subject Headings (MeSH). 2026. Unique ID D016723. http://id.nlm.nih.gov/mesh/2026/D016723
- Bone Remodeling. In: Wikipedia. https://en.wikipedia.org/wiki/Bone_remodeling
- Bone Remodeling. In: Wikidata. https://www.wikidata.org/wiki/Q952019