Chemicals and Drugs

Biotin

A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.

Chemical Identity

Chemical Information

Molecular Formula
C10H16N2O3S
Molecular Weight
244.31 g/mol
CAS Registry No.
58-85-5
IUPAC Name
5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid
InChIKey
YBJHBAHKTGYVGT-ZKWXMUAHSA-N
SMILES
C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)O)NC(=O)N2
MeSH Unique ID
D001710
Source
PubChem CID 171548

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

16 entry terms
  • Vitamin H
  • Biodermatin
  • Biokur
  • Biotin Gelfert
  • Biotin Hermes
  • Biotin-Ratiopharm
  • Biotine Roche
  • Deacura
  • Gabunat
  • Medebiotin
  • Medobiotin
  • Rombellin
  • Biotin Ratiopharm
  • Gelfert, Biotin
  • Hermes, Biotin
  • Roche, Biotine

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/ther use: coordinate disease with /drug ther, not /diet ther; deficiency: coordinate BIOTIN /defic (IM) with VITAMIN B DEFICIENCY (IM)

MeSH Hierarchy

Tree Numbers

  1. D03w.383.129w.308.080w
  2. D08.211w.096w

MeSH Record

NLM Classification

QU 187

AMA Style

References

  1. National Library of Medicine. Biotin. Medical Subject Headings (MeSH). 2026. Unique ID D001710. http://id.nlm.nih.gov/mesh/2026/D001710
  2. Biotin. In: Wikipedia. https://en.wikipedia.org/wiki/Biotin
  3. Biotin. In: Wikidata. https://www.wikidata.org/wiki/Q181354
  4. Biotin. In: PubChem Compound. CID 171548. https://pubchem.ncbi.nlm.nih.gov/compound/171548