Chemicals and Drugs

Biliverdine

1,3,6,7-Tetramethyl-4,5-dicarboxyethyl-2,8-divinylbilenone. Biosynthesized from hemoglobin as a precursor of bilirubin. Occurs in the bile of AMPHIBIANS and of birds, but not in normal human bile or serum.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

1,3,6,7-Tetramethyl-4,5-dicarboxyethyl-2,8-divinylbilenone. Biosynthesized from hemoglobin as a precursor of bilirubin. Occurs in the bile of AMPHIBIANS and of birds, but not in normal human bile or serum.

Chemical Identity

Chemical Information

Molecular Formula
C33H34N4O6
Molecular Weight
582.6 g/mol
CAS Registry No.
114-25-0
IUPAC Name
3-[(2Z,5Z)-2-[[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methylidene]-5-[(4-ethenyl-3-methyl-5-oxopyrrol-2-yl)methylidene]-4-methylpyrrol-3-yl]propanoic acid
InChIKey
RCNSAJSGRJSBKK-NSQVQWHSSA-N
SMILES
CC\1=C(/C(=C/C2=C(C(=C(N2)/C=C\3/C(=C(C(=O)N3)C)C=C)C)CCC(=O)O)/N/C1=C\C4=NC(=O)C(=C4C)C=C)CCC(=O)O
MeSH Unique ID
D001664
Source
PubChem CID 5280353

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

9 entry terms
  • Biliverdin
  • Dehydrobilirubin
  • Ooecyan
  • Uteroverdine
  • Biliverdin IX
  • Biliverdin IX alpha
  • IX alpha, Biliverdin
  • IX, Biliverdin
  • alpha, Biliverdin IX

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

a bile pigment in amphibia & birds but not in normal human bile; /biosyn /physiol permitted

MeSH Record

History Note

91(76); was see under BILIRUBIN 1976-90

MeSH Record

Previous Indexing

  • Bilirubin (1969-1975)

MeSH Hierarchy

Tree Numbers

  1. D03w.383.129w.578.840w.249w.184w.200w
  2. D03w.633.400.909w.249w.184w.200w
  3. D04w.345w.783w.249w.184w.200w
  4. D23.767w.193w.184w.200w

AMA Style

References

  1. National Library of Medicine. Biliverdine. Medical Subject Headings (MeSH). 2026. Unique ID D001664. http://id.nlm.nih.gov/mesh/2026/D001664
  2. Biliverdine. In: Wikipedia. https://en.wikipedia.org/wiki/Biliverdin
  3. Biliverdine. In: Wikidata. https://www.wikidata.org/wiki/Q422964
  4. Biliverdine. In: PubChem Compound. CID 5280353. https://pubchem.ncbi.nlm.nih.gov/compound/5280353