Chemicals and Drugs

Bepridil

A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.

Chemical Identity

Chemical Information

Molecular Formula
C24H34N2O
Molecular Weight
366.5 g/mol
CAS Registry No.
64706-54-3
IUPAC Name
N-benzyl-N-[3-(2-methylpropoxy)-2-pyrrolidin-1-ylpropyl]aniline
InChIKey
UIEATEWHFDRYRU-UHFFFAOYSA-N
SMILES
CC(C)COCC(CN(CC1=CC=CC=C1)C2=CC=CC=C2)N3CCCC3
MeSH Unique ID
D015764
Source
PubChem CID 2351

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

22 entry terms
  • 1978-CERM
  • Bedapin
  • Bepadin
  • Bepridil Monohydrochloride
  • Bepridil Monohydrochloride, Monohydrate
  • Bepridil Monohydrochloride, alpha-Isomer
  • Bepridil, (+)-Isomer
  • Bepridil, (+-)-Isomer
  • Bepridil, (-)-Isomer
  • Bepridil, alpha-Isomer
  • CERM-1978
  • Cordium
  • Unicordium
  • Vascor
  • 1978 CERM
  • 1978CERM
  • Bepridil Monohydrochloride, alpha Isomer
  • Bepridil, alpha Isomer
  • CERM 1978
  • CERM1978
  • Monohydrochloride, Bepridil
  • Monohydrochloride, alpha-Isomer Bepridil

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Anti-Arrhythmia Agents (1976-1989)
  • Antihypertensive Agents (1966-1989)
  • Calcium Channel Blockers (1982-1989)
  • Pyrrolidines (1966-1989)

MeSH Hierarchy

Tree Number

  1. D03w.383.773.107w

AMA Style

References

  1. National Library of Medicine. Bepridil. Medical Subject Headings (MeSH). 2026. Unique ID D015764. http://id.nlm.nih.gov/mesh/2026/D015764
  2. Bepridil. In: Wikipedia. https://en.wikipedia.org/wiki/Bepridil
  3. Bepridil. In: Wikidata. https://www.wikidata.org/wiki/Q4890934
  4. Bepridil. In: PubChem Compound. CID 2351. https://pubchem.ncbi.nlm.nih.gov/compound/2351