Structured Summary
Abstract
A centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISEASE. Benztropine also inhibits the uptake of dopamine.
Chemical Identity
Chemical Information
- Molecular Formula
- C21H25NO
- Molecular Weight
- 307.4 g/mol
- CAS Registry No.
- 86-13-5
- IUPAC Name
- (1R,5S)-3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane
- InChIKey
- GIJXKZJWITVLHI-YOFSQIOKSA-N
- SMILES
- CN1[C@@H]2CC[C@H]1CC(C2)OC(C3=CC=CC=C3)C4=CC=CC=C4
- MeSH Unique ID
- D001590
- Source
- PubChem CID 1201549
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
21 entry terms
- Benzatropine
- Apo-Benztropine
- Bensylate
- Benzatropine Mesylate
- Benzatropine Methanesulfonate
- Benzatropine Methanesulfonate, Hydrobromide
- Benzatropine Methanesulfonate, Hydrobromide, (endo)-Isomer
- Benzatropine Methanesulfonate, Hydrochloride, (endo)-Isomer
- Benztropine Mesylate
- Cogentin
- Cogentinol
- N-Methylbenztropine
- PMS-Benztropine
- Apo Benztropine
- Hydrobromide Benzatropine Methanesulfonate
- Mesylate, Benzatropine
- Mesylate, Benztropine
- Methanesulfonate, Benzatropine
- Methanesulfonate, Hydrobromide Benzatropine
- N Methylbenztropine
- PMS Benztropine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
1991(1972); use TROPANES 1972-1990
MeSH Record
Previous Indexing
- Tropanes (1972-1990)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Benztropine. Medical Subject Headings (MeSH). 2026. Unique ID D001590. http://id.nlm.nih.gov/mesh/2026/D001590
- Benztropine. In: Wikipedia. https://en.wikipedia.org/wiki/Benzatropine
- Benztropine. In: Wikidata. https://www.wikidata.org/wiki/Q415026
- Benztropine. In: PubChem Compound. CID 1201549. https://pubchem.ncbi.nlm.nih.gov/compound/1201549