Chemicals and Drugs

Benzoylarginine-2-Naphthylamide

An enzyme substrate which permits the measurement of peptide hydrolase activity, e.g. trypsin and thrombin. The enzymes liberate 2-naphthylamine, which is measured by colorimetric procedures.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme substrate which permits the measurement of peptide hydrolase activity, e.g. trypsin and thrombin. The enzymes liberate 2-naphthylamine, which is measured by colorimetric procedures.

Chemical Identity

Chemical Information

Molecular Formula
C23H25N5O2
Molecular Weight
403.5 g/mol
CAS Registry No.
24000-95-1
IUPAC Name
N-[(2S)-5-(diaminomethylideneamino)-1-(naphthalen-2-ylamino)-1-oxopentan-2-yl]benzamide
InChIKey
DEFAKPKFXYITPZ-FQEVSTJZSA-N
SMILES
C1=CC=C(C=C1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NC2=CC3=CC=CC=C3C=C2
MeSH Unique ID
D001587
Source
PubChem CID 6999973

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

6 entry terms
  • Benzoylarginine 2 Naphthylamide
  • Benzoylarginine beta-Naphthylamide
  • 2 Naphthylamide, Benzoylarginine
  • Benzoylarginine beta Naphthylamide
  • Naphthylamide, Benzoylarginine 2
  • beta-Naphthylamide, Benzoylarginine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(77); was see under ARGININE 1977-90; was BENZOYLARGININE BETA NAPHTHYLAMIDE see under ARGININE 1976

MeSH Record

Previous Indexing

  • Arginine (1973-1974) /analogs & derivatives (1975)
  • Benzamides (1974-1975)
  • Naphthalenes (1973-1975)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.300
  2. D12.125w.068.050w.095
  3. D12.125w.095w.104w.095

AMA Style

References

  1. National Library of Medicine. Benzoylarginine-2-Naphthylamide. Medical Subject Headings (MeSH). 2026. Unique ID D001587. http://id.nlm.nih.gov/mesh/2026/D001587
  2. Benzoylarginine-2-Naphthylamide. In: Wikidata. https://www.wikidata.org/wiki/Q27162712
  3. Benzoylarginine-2-Naphthylamide. In: PubChem Compound. CID 6999973. https://pubchem.ncbi.nlm.nih.gov/compound/6999973