Chemicals and Drugs

Batroxobin

A proteolytic enzyme obtained from the venom of fer-de-lance (BOTHROPS ATROX). It is used as a plasma clotting agent for fibrinogen and for the detection of fibrinogen degradation products. The presence of heparin does not interfere with the clotting test. Hemocoagulase is a mixture containing batroxobin and factor X activator. EC 3.4.21.-.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A proteolytic enzyme obtained from the venom of fer-de-lance (BOTHROPS ATROX). It is used as a plasma clotting agent for fibrinogen and for the detection of fibrinogen degradation products. The presence of heparin does not interfere with the clotting test. Hemocoagulase is a mixture containing batroxobin and factor X activator. EC 3.4.21.-.

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • Defibrol
  • Defibrase
  • Hemocoagulase
  • Reptilase
  • Reptilase-DEF
  • Reptilase DEF

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2000(1975); for PLASMOCOAGULASE use BATROXOBIN (NM) 1979-1999

MeSH Record

Previous Indexing

  • Peptide Hydrolases (1969-1974)
  • Snakes (1969-1974)
  • Venoms (1969-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Batroxobin. Medical Subject Headings (MeSH). 2026. Unique ID D012103. http://id.nlm.nih.gov/mesh/2026/D012103
  2. Batroxobin. In: Wikipedia. https://en.wikipedia.org/wiki/Batroxobin
  3. Batroxobin. In: Wikidata. https://www.wikidata.org/wiki/Q993771