Phenomena and Processes

Base Pair Mismatch

The presence of an non-complementary base in double-stranded DNA (DNA mismatch) caused by spontaneous deamination of cytosine or adenine, mismatching during homologous recombination, small insertions or deletions, or errors in DNA replication. Multiple, sequential base pair mismatches lead to formation of heteroduplex DNA; (NUCLEIC ACID HETERODUPLEXES).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The presence of an non-complementary base in double-stranded DNA (DNA mismatch) caused by spontaneous deamination of cytosine or adenine, mismatching during homologous recombination, small insertions or deletions, or errors in DNA replication. Multiple, sequential base pair mismatches lead to formation of heteroduplex DNA; (NUCLEIC ACID HETERODUPLEXES).

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Classification

Broader headings

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See Also

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Synonyms

3 entry terms
  • Base Pair Mismatches
  • Mismatch, Base Pair
  • Mismatches, Base Pair

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Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

1999

MeSH Hierarchy

Tree Numbers

  1. G05.200w.052
  2. G05.365w.590w.060

AMA Style

References

  1. National Library of Medicine. Base Pair Mismatch. Medical Subject Headings (MeSH). 2026. Unique ID D020137. http://id.nlm.nih.gov/mesh/2026/D020137
  2. Base Pair Mismatch. In: Wikidata. https://www.wikidata.org/wiki/Q71130381