Structured Summary
Abstract
An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION.
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Synonyms
17 entry terms
- Antigens, CD274
- B7-H1 Immune Costimulatory Protein
- B7H1 Immune Costimulatory Protein
- CD274 Antigen
- PD-L1 Costimulatory Protein
- PD-L1 Protein
- Programmed Cell Death 1 Ligand 1
- Programmed Cell Death 1 Ligand 1 Protein
- Programmed Death Ligand 1
- Antigen, B7-H1
- Antigen, CD274
- B7 H1 Antigen
- B7 H1 Immune Costimulatory Protein
- CD274 Antigens
- Costimulatory Protein, PD-L1
- PD L1 Costimulatory Protein
- PD L1 Protein
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2018 (2007)
MeSH Record
Previous Indexing
- Antigens, CD (2007-2011)
- Antigens, CD80 (2001-2006)
- Blood Proteins (2001-2005)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. B7-H1 Antigen. Medical Subject Headings (MeSH). 2026. Unique ID D060890. http://id.nlm.nih.gov/mesh/2026/D060890
- B7-H1 Antigen. In: Wikipedia. https://en.wikipedia.org/wiki/PD-L1
- B7-H1 Antigen. In: Wikidata. https://www.wikidata.org/wiki/Q21100639